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Article

Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis.

The EMBO journal - 3 Feb 1997

Desaintes C, Demeret C, Goyat S, Yaniv M, Thierry F

Abstract excerpt

The papillomavirus E2 protein plays a central role in the viral life cycle as it regulates both transcription and replication of the viral genome. In this study, we showed that transient expression of bovine papillomavirus type 1 or human papillomavirus type 18 (HPV18) E2 proteins in HeLa cells activated the transcriptional activity of p53 through at least two pathways. The first one involved the binding of E2 to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9034333
DOI: 10.1093/emboj/16.3.504
PMCID: PMC1169654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis.PMID 9034333Read ↗

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