Article
Linkage analysis of Tourette syndrome in a large Utah pedigree.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Knight Stacey, Coon Hilary, Johnson Michael, Leppert Mark F, Camp Nicola J, McMahon William M
Abstract excerpt
Tourette syndrome (TS) is a neuropsychiatric disorder characterized by multiple motor and phonic tics. The heritability of TS has been well established, yet there is a lack of consensus in genome-wide linkage studies. The purpose of this study was to conduct a genome-wide linkage analysis on a unique, large, high-risk TS Utah pedigree. We examined a qualitative trait (TS1) where cases had a definitive diagnosis...
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