Article
RANTES in human allergen-induced rhinitis: cellular source and relation to tissue eosinophilia.
American journal of respiratory and critical care medicine - 1 Feb 1997
Rajakulasingam K, Hamid Q, O'Brien F, Shotman E, Jose P J, Williams T J, Jacobson M, Barkans J, Durham S R
Abstract excerpt
Human allergen-induced rhinitis is associated with recruitment and activation of CD4+ T lymphocytes and eosinophils. RANTES is a novel CC chemokine that is a potent chemoattractant for both memory T cells and eosinophils. We therefore investigated RANTES in the nasal mucosa after local allergen provocation. Nasal lavage was performed, and biopsies from the inferior nasal turbinate were taken from 14 atopic,...
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