Article
Krüppel, a Drosophila segmentation gene, participates in the specification of neurons and glial cells.
Mechanisms of development - 1 Nov 1996
Romani S, Jimenez F, Hoch M, Patel N H, Taubert H, Jäckle H
Abstract excerpt
We report that the Drosophila segmentation gene Krüppel (Kr) is expressed in neural precursor cells, neurons and glial cells at different stages of neurogenesis and that Kr mutants develop aberrant peripheral (PNS) and central (CNS) nervous systems. Expression derived from a Kr minigene rescues t...
Topics
- Animals
- Central Nervous System
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Fluorescent Antibody Technique, Indirect
- Genes, Insect
- Immunohistochemistry
- Kruppel-Like Transcription Factors
- Microscopy, Confocal
- Mutation