Article
Haptoglobin phenotypes and gene frequencies in bipolar disorder: an association study in family-history subgroups.
Human heredity - 1 Jan 2000
Fãnanás L, Moral P, Gutiérrez B, Guillamat R, Vallés V, Campillo M, Gutiérrez-Pacheco B, Lütken N, Bertranpetit J
Abstract excerpt
Several studies have shown that major depression is accompanied by significantly increased plasma levels of positive acute-phase proteins such as haptoglobin (Hp). A significant higher frequency of the HP*1 allele has recently been detected in patients with unipolar major depression. Pursuing the hypothesis that certain unipolar and bipolar disorders may be genetically related, this study analyzed Hp genotype and...
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