Article
Depression, delusions, and hallucinations in Alzheimer's disease: no relationship to apolipoprotein E genotype.
The Journal of neuropsychiatry and clinical neurosciences - 1 Jan 1997
Lyketsos C G, Baker L, Warren A, Steele C, Brandt J, Steinberg M, Kopunek S, Baker A
Abstract excerpt
The apolipoprotein E (APOE) locus on chromosome 19 has been shown to modify risk, and age at onset, of Alzheimer's disease (AD). The authors hypothesized that the phenotypic expression of different psychiatric symptoms in patients with AD would be associated with variability in APOE locus. Neuropsychiatric and genetic testing of 120 probable AD patients revealed 28% had major depression, 17% had minor depression,...
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