Article
Tissue and Species Distribution of mRNA for the i<sub>kr</sub>-like K<sup>+</sup>Channel, ERG
1 Feb 1997
Abstract excerpt
The human K+ channel gene, HERG, has been linked to the type 2 form of the autosomal dominant long-QT syndrome and has been suggested to encode the fast component of the delayed rectifier K+ current (IKr) found in heart. To date, the published electrophysiological and pharmacological data on the Xenopus-expressed HERG are very similar but are not identical to those of the endogenous IKr. In an effort to provide a...
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