Article
Neuropeptide amidation in Drosophila: separate genes encode the two enzymes catalyzing amidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Feb 1997
Kolhekar A S, Roberts M S, Jiang N, Johnson R C, Mains R E, Eipper B A, Taghert P H
Abstract excerpt
In vertebrates, the two-step peptide alpha-amidation reaction is catalyzed sequentially by two enzymatic activities contained within one bifunctional enzyme called PAM (peptidylglycine alpha-amidating mono-oxygenase). Drosophila head extracts contained both of these PAM-related enzyme activities:...
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