Article
High-affinity binding of laurate to naturally occurring mutants of human serum albumin and proalbumin.
The Biochemical journal - 15 Dec 1996
Kragh-Hansen U, Pedersen A O, Galliano M, Minchiotti L, Brennan S O, Tárnoky A L, Franco M H, Salzano F M
Abstract excerpt
Binding of laurate (n-dodecanoate) to genetic variants of albumin or its proprotein and to normal albumin isolated from the same heterozygous carriers was studied by a kinetic dialysis technique at physiological pH. The first stoichiometric association constant for binding to proalbumin Lille (Ar...
Topics
- Amino Acid Sequence
- Dialysis
- Glycosylation
- Humans
- Kinetics
- Lauric Acids
- Molecular Sequence Data
- Mutation
- Point Mutation
- Prealbumin
- Protein Binding
- Serum Albumin