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Article

Site-directed mutagenesis of alpha II spectrin at codon 1175 modulates its mu-calpain susceptibility.

Biochemistry - 7 Jan 1997

Stabach P R, Cianci C D, Glantz S B, Zhang Z, Morrow J S

Abstract excerpt

Intracellular proteolysis by the calpains, a family of Ca2+ activated cysteine proteases, is a ubiquitous yet poorly understood process. Their action is implicated in an array of cellular and pathologic processes, including long-term potentiation, synaptic remodeling, protein kinase C and steroid receptor activation, ischemic cellular injury, and apoptosis. Unlike most proteases, the calpains display unusually...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8993318
DOI: 10.1021/bi962034i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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