Article
The normal and abnormal genes of the a and b subunits in coagulation factor XIII.
Seminars in thrombosis and hemostasis - 1 Jan 1996
Ichinose A, Izumi T, Hashiguchi T
Abstract excerpt
Factor XIII consists of two catalytic a and two noncatalytic b subunits. The gene for the a subunit is located on chromosome 6, the gene for the b subunit on chromosome 1. Both genes have been characterized. There are several different allelic forms of the a subunit in the normal population and some microheterogeneity for the b subunit. Most patients with congenital factor XIII deficiency lack the a subunit in...
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