Molecular basis for subtypic differences of the "a" subunit of coagulation factor XIII with description of the genesis of the subtypes.

doi:10.1007/BF00202857

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Article

Molecular basis for subtypic differences of the "a" subunit of coagulation factor XIII with description of the genesis of the subtypes.

Human genetics - 1 Aug 1994

Suzuki K, Iwata M, Ito S, Matsui K, Uchida A, Mizoi Y

Abstract excerpt

The "a" subunit of human coagulation factor XIII (F13A) exhibits genetic polymorphism defined by four common alleles, F13A*1A, *1B, *2A, and *2B. We have previously suggested on the basis of the isoelectric focusing patterns of the four allele products that point mutations at two separate sites a...

Topics

Alleles
Base Sequence
Exons
Factor XIII
Genotype
Humans
Isoelectric Focusing
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length

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