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Article

A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinoma

2023-08-06

Abstract excerpt

Xp11 translocation renal cell carcinoma (tRCC) is a female-predominant kidney cancer driven by translocations between the TFE3 gene on chromosome Xp11.2 and partner genes located on either chrX or on autosomes. The rearrangement processes that underlie TFE3 fusions, and whether they are linked to the female sex bias of this cancer, are largely unexplored. Moreover, whether oncogenic TFE3 fusions arise from both...

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Literature Corpus work
42bedc51-e585-503a-a012-f43f43f5d115
DOI
10.1101/2023.08.04.552029
Open publication

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A genetic basis for cancer sex differences revealed in Xp11 translocation renal cell carcinomaDOI 10.1101/2023.08.04.552029
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