Article
11 beta-Hydroxysteroid dehydrogenase and its role in the syndrome of apparent mineralocorticoid excess.
Pediatric research - 1 Jan 1997
White P C, Mune T, Rogerson F M, Kayes K M, Agarwal A K
Abstract excerpt
Aldosterone, the most important mineralocorticoid, regulates electrolyte excretion and intravascular volume mainly through its effects on renal distal tubules and cortical collecting ducts, where it acts to increase sodium resorption from and potassium excretion into the urine. Excess secretion o...
Topics
- 11-beta-Hydroxysteroid Dehydrogenases
- Cloning, Molecular
- DNA, Complementary
- Humans
- Hydroxysteroid Dehydrogenases
- Hypertension
- Isoenzymes
- Mineralocorticoids
- Mutation
- Syndrome