Article
Mitochondrial diseases.
Best practice & research. Clinical obstetrics & gynaecology - 1 Oct 2002
Graff Caroline, Bui The-Hung, Larsson Nils-Göran
Abstract excerpt
Mitochondrial disorders are caused by deficient respiratory chain function, resulting in a complex series of pathophysiological events. Genetic counselling is complicated because the respiratory chain subunits are encoded by both nuclear and mitochondrial DNA genes. Only a minority of the nuclear genes involved in mitochondrial function have been identified, and even fewer are associated with human mitochondrial...
Read the complete abstract on PubMedTopics
- DNA, Mitochondrial
- Female
- Fetal Diseases
- Genetic Counseling
- Humans
- Mitochondrial Diseases
- Mutation