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Article

Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180).

1 Dec 1996

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 8967966
DOI: 10.1016/s0026-895x(25)09603-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180).PMID 8967966Read ↗

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DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial DrugsSemantic proximity Read ↗

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Drug resistance associated with altered DNA topoisomerase II.Semantic proximity Read ↗

Topoisomerase IIα, rather than IIβ, is a promising target in development of anti-cancer drugsSemantic proximity Read ↗

Use of CRISPR/Cas9 with Homology-Directed Repair to Gene-Edit Topoisomerase IIβ in Human Leukemia K562 Cells: Generation of a Resistance Phenotype.Semantic proximity Read ↗

Discovery and development of kibdelomycin, a new class of broad-spectrum antibiotics targeting the clinically proven bacterial type II topoisomeraseSemantic proximity Read ↗

Novel HeLa topoisomerase II is the IIβ isoform: complete coding sequence and homology with other type II topoisomerasesSemantic proximity Read ↗

Clinical resistance to topoisomerase-targeted drugsSemantic proximity Read ↗

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