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Article

[Inter-generational transmission of mutations responsible for fragile X syndrome].

Pediatria polska - 1 Mar 1996

Milewski M, Bal J, Mazurczak T

Abstract excerpt

Inter-generational transmission of normal and mutated (CGG)n sequences in the FMR1 gene was studied in 17 Polish fragile X families. All normal alleles were stable when transmitted to the progeny. Twenty-five of the 26 transmitted maternal premutations expanded to full mutation level. No correlation between the number of CGG repeats in the maternal premutation and the size of the mutation in the offspring was...

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Source

Identifiers

PMID: 8966089

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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[Inter-generational transmission of mutations responsible for fragile X syndrome].PMID 8966089Read ↗

Expansion to full mutation of a FMR1 intermediate allele over two generations.Semantic proximity Read ↗

Familial transmission of the FMR1 CGG repeat.Semantic proximity Read ↗

Paternal transmission of a FMR1 full mutation allele.Semantic proximity Read ↗

Prenatal diagnosis of fragile X syndrome and the risk of expansion of a premutation.Semantic proximity Read ↗

Expansion of an FMR1 grey-zone allele to a full mutation in two generations.Semantic proximity Read ↗

Expansion of the fragile X CGG repeat in females with premutation or intermediate alleles.Semantic proximity Read ↗

Transmission of an FMR1 premutation allele in a large family identified through newborn screening: the role of AGG interruptions.Semantic proximity Read ↗

Analysis of unstable DNA sequence in FMR1 gene in Polish families with fragile X syndrome.Semantic proximity Read ↗

Expansion of the CGG repeat in fragile X in the FMR1 gene depends on the sex of the offspring.Semantic proximity Read ↗

[Significance and case analysis of FMR1 mutation screening during early and middle pregnancy].Semantic proximity Read ↗

AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome.Semantic proximity Read ↗

Genetic variation and intergenerational FMR1 CGG-repeat stability in 100 unrelated three-generation families from the normal population.Semantic proximity Read ↗

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