Article
Familial transmission of the FMR1 CGG repeat.
American journal of human genetics - 1 Dec 1996
Nolin S L, Lewis F A, Ye L L, Houck G E, Glicksman A E, Limprasert P, Li S Y, Zhong N, Ashley A E, Feingold E, Sherman S L, Brown W T
Abstract excerpt
To better define the nature of FMR1 CGG-repeat expansions, changes in allele sizes for 191 families with fragile X and for 33 families with gray-zone repeats (40-60) were analyzed. Expansion of the fragile X chromosome to the full mutation was seen in 13.4% of offspring from premutation mothers with 56-59 repeats, 20.6% of those with 60-69 repeats, 57.8% of those with 70-79 repeats, 72.9% of those with 80-89...
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