Article
Overexpression of p53 in tall cell variants of papillary thyroid carcinoma.
Surgery - 1 Dec 1996
Rüter A, Dreifus J, Jones M, Nishiyama R, Lennquist S
Abstract excerpt
BACKGROUND: The tall cell variant (TCV) is a clinically aggressive subtype of papillary thyroid cancer. The aim of this study was to discover the prevalence of mutant forms of p53 protein in this subtype and relate it to clinical outcome. METHODS: Eighteen patients with TCV and a control group with common papillary cancers, matched for age and gender, were studied. The p53 mutations were identified by means of...
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