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Article

Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT.

Endocrine-related cancer - 1 Jun 2015

Dettmer Matthias S, Schmitt Anja, Steinert Hans, Capper David, Moch Holger, Komminoth Paul, Perren Aurel

Abstract excerpt

The tall cell (TC) variant of papillary thyroid carcinoma (PTC) has an unfavorable prognosis. The diagnostic criteria remain inconsistent, and the role of a minor TC component is unclear. Molecular diagnostic markers are not available; however, there are two potential candidates: BRAF V600E and telomerase reverse transcriptase (TERT) promoter mutations. Using a novel approach, we enriched a collective with PTCs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 25870252
DOI: 10.1530/ERC-15-0057

Genes

BRAF
TERT

Variants

Provenance

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