Article
Genomic instability in ovarian cancer: a reassessment using an arbitrarily primed polymerase chain reaction.
Oncogene - 5 Dec 1996
Sood A K, Buller R E
Abstract excerpt
Traditional polymerase chain reaction (PCR) amplification of multiple microsatellite markers to detect microsatellite instability (MI) is labor intensive and may be marker dependent. An arbitrarily primed polymerase chain reaction (AP-PCR) is a modification of PCR that generates a genomic DNA fingerprint using a single, arbitrarily chosen primer which is useful in the detection of somatic genetic alterations. We...
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