Article
Study of aspartate at residue 9 of HLA-C molecules in Japanese patients with psoriasis vulgaris.
Journal of dermatological science - 1 Nov 1996
Asahina A, Kuwata S, Tokunaga K, Juji T, Nakagawa H
Abstract excerpt
The frequency of aspartate at residue 9 (Asp-9) of HLA-C molecules was investigated among 75 Japanese patients with psoriasis vulgaris and 50 healthy controls. We developed a technique of polymerase chain reaction sequence-specific primer (PCR-SSP) amplification of genomic DNA for HLA-C alleles with a codon for Asp-9. The specificity of amplification was confirmed by direct sequencing of the amplified products...
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