Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific nucleotide sequence of HLA-C is strongly associated with psoriasis vulgaris.

The Journal of investigative dermatology - 1 Aug 1991

Asahina A, Akazaki S, Nakagawa H, Kuwata S, Tokunaga K, Ishibashi Y, Juji T

Abstract excerpt

The association of specific HLA-C nucleotide sequences with psoriasis vulgaris was investigated in 75 Japanese patients by the polymerase chain reaction method, followed by slot-blot hybridization using two specific oligonucleotide probes. The synthesized nucleotide primers were C180P, 5'-GACCGGGAGACACAGAAGTACAAG-3' (coding for amino acid residues 61 to 68 of the alpha 1 domain of the HLA-C molecule) and C243PR,...

Topics

Alanine
Alleles
Base Sequence
Codon
DNA
Female
Gene Amplification
HLA-C Antigens
Humans
Male
Molecular Sequence Data
Nucleic Acid Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotide Probes

Polymerase Chain Reaction

Psoriasis

Source

Identifiers

PMID: 2071937
DOI: 10.1111/1523-1747.ep12480361

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2071937-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific nucleotide sequence of HLA-C is strongly associated with psoriasis vulgaris.PMID 2071937Read ↗

Do specific pockets of HLA-C molecules predispose Jewish patients to psoriasis vulgaris?Semantic proximity Read ↗

Study of aspartate at residue 9 of HLA-C molecules in Japanese patients with psoriasis vulgaris.Semantic proximity Read ↗

Analysis of HLA class II and TAP alleles in Japanese patients with psoriasis vulgaris.Semantic proximity Read ↗

A peculiar sequence motif in the alpha-1-domain of the HLA-C molecule in psoriasis.Semantic proximity Read ↗

HLA-DRB1*0701 and DRB1*1401 are associated with genetic susceptibility to psoriasis vulgaris in a Taiwanese population.Semantic proximity Read ↗

Role of HLA-B and C alleles in development of psoriasis in patients from North India.Semantic proximity Read ↗

Distribution of the CTLA-4 single nucleotide polymorphisms CT60G>A and +49A>G in psoriasis vulgaris patients and control individuals from a Polish Caucasian population.Semantic proximity Read ↗

HLA-CW*0602 is a susceptibility factor in type I psoriasis, and evidence Ala-73 is increased in male type I psoriatics.Semantic proximity Read ↗

HLA class I and II alleles and susceptibility to generalized pustular psoriasis: significant associations with HLA-Cw1 and HLA-DQB1*0303.Semantic proximity Read ↗

Association of HLA class I and class II alleles with psoriasis vulgaris in Turkish population. Influence of type I and II psoriasis.Semantic proximity Read ↗

HLA risk haplotype Cw6,DR7,DQA1*0201 and HLA-Cw6 with reference to the clinical picture of psoriasis vulgaris.Semantic proximity Read ↗

A possible relationship of human leucocyte antigens with psoriasis vulgaris and geographic tongue.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.