Article
Molecular characterization of 21p- variant chromosome.
Clinical genetics - 1 Aug 1996
Conte R A, Mathews T, Kleyman S M, Verma R S
Abstract excerpt
Fortuitously, within a 1-month period, we were referred two individuals for routine cytogenetic amniocenteses involving one chromosome 21 from each patient, which had apparently lost the entire short arm and a major portion of the centromeric alphoid sequences in their amniocytes. Breakage may ha...
Topics
- Amniocentesis
- Chromosome Aberrations
- Chromosomes, Human, Pair 21
- Female
- Genetic Variation
- Humans
- In Situ Hybridization
- Karyotyping
- Lymphocytes
- Male
- Middle Aged
- Pregnancy