Article
A rare heteromorphism of chromosome 20 and reproductive loss.
Journal of medical genetics - 1 Jul 1991
Romain D R, Whyte S, Callen D F, Eyre H J
Abstract excerpt
A rare centromeric heterochromatic variant of chromosome 20 was encountered during investigations in a couple with repeated miscarriages. The enlarged segment was G and C band positive and stained positively by Giemsa II. In situ hybridisation of the biotinylated alphoid probe D20Z1 specific for the centromere of chromosome 20 to metaphase cells confirmed the presence of amplified sequences adjacent to the...
Topics
- Abortion, Habitual
- Adolescent
- Centromere
- Chromosomes, Human, Pair 20
- Female
- Genetic Variation
- Humans
- Male
- Nucleic Acid Hybridization
- Pregnancy