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Article

Bacterial production of transdihydroxycyclohexadiene carboxylates by metabolic pathway engineering.

Microbiology (Reading, England) - 1 Apr 1996

Müller Rolf, Breuer Michael, Wagener Andreas, Schmidt Karsten, Leistner Eckhard

Abstract excerpt

Homochiral-cis-cyclohexa-3,5-diene-1,2-diols are important synthons. We found a way to produce trans-configured homochiral diols using recombinant Klebsiella pneumoniae 62-1. Transformation of this mutant (Phe- Trp- Tyr-) with plasmids carrying genes involved in chorismic and isochorismic acid metabolism leads to the production of either (+)-trans-(2S,3S)-2,3-dihydroxycyclohexa-4,6-dienecarboxylic acid or...

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PMID: 8936326
DOI: 10.1099/00221287-142-4-1005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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