Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of ubiquitin carboxyl terminal hydrolase in the differentiation of human acute lymphoblastic leukemia cell line, Reh.

Differentiation; research in biological diversity - 1 Mar 1996

Maki A, Mohammad R M, Smith M, Al-Katib A

Abstract excerpt

We have previously demonstrated that the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA), induces differentiation of the acute lymphoblastic leukemia cell line, Reh, to a mature non-dividing state. Associated with this differentiation is the expression of ubiquitin carboxyl terminal hydrolase (UCH-L1). To investigate the role of UCH-L1 in TPA-induced Reh differentiation and apoptosis, molecular and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Apoptosis
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Phenotype

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Tetradecanoylphorbol Acetate

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 8935929
DOI: 10.1046/j.1432-0436.1996.6010059.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Role of ubiquitin carboxyl terminal hydrolase in the differentiation of human acute lymphoblastic leukemia cell line, Reh.PMID 8935929Read ↗

Induced expression of a monocytoid B lymphocyte antigen phenotype on the REH cell line.Semantic proximity Read ↗

Neuroblastoma cell apoptosis induced by the synthetic retinoid N‐(4‐hydroxyphenyl)retinamideSemantic proximity Read ↗

Administration of a phorbol ester to patients with hematological malignancies: preliminary results from a phase I clinical trial of 12-O-tetradecanoylphorbol-13-acetate.Semantic proximity Read ↗

Retrodifferentiation and rejuvenation of senescent monocytic cells requires PARP-1.Semantic proximity Read ↗

Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation.Semantic proximity Read ↗

Phorbol ester induces apoptosis in HL-60 promyelocytic leukemia cells but not in HL-60 PET mutant.Semantic proximity Read ↗

Tissue transglutaminase-dependent posttranslational modification of the retinoblastoma gene product in promonocytic cells undergoing apoptosis.Semantic proximity Read ↗

Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.