Article
Association between the PI*M3 allele of alpha 1-antitrypsin and Alzheimer's disease? A preliminary report.
Human genetics - 1 Dec 1996
Kowalska A, Danker-Hopfe H, Wender M, Florczak J, Walter H
Abstract excerpt
The deposition of beta A4-amyloid in senile plaques in the brain and small cerebral vessels is one of the pathological hallmarks of Alzheimer's disease (AD). Serine protease inhibitors (serpins) such as alpha 1-antitrypsin and alpha 1-antichymotrypsin have been found to be associated with beta-am...
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