Alpha-1-antitrypsin (PI) polymorphism in France, with special regard to the PI*Z allele.

doi:10.1159/000154022

Back to search

Article

Alpha-1-antitrypsin (PI) polymorphism in France, with special regard to the PI*Z allele.

Human heredity - 1 Jan 1991

Sesboüé R, Martin J P

Abstract excerpt

Alpha-1-antitrypsin (PI) phenotypes were studied in a sample of more than 5,000 individuals from cities throughout France. Special interest was paid to the PI*Z allele whose average frequency, based on the present work plus results from the literature, was 0.0130. This figure was used to estimate...

Topics

Adult
Air Pollutants, Occupational
Alleles
Female
France
Gene Frequency
Humans
Male
Middle Aged
Mutation
Phenotype
Polymorphism, Genetic
Respiratory Tract Diseases
Risk Factors
alpha 1-Antitrypsin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.