Article
T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4 <sup>+</sup> T Cell Turnover
29 Nov 1996
Abstract excerpt
Progression to acquired immunodeficiency syndrome (AIDS) has been related to exhaustion of the regenerative capacity of the immune system resulting from high T cell turnover. Analysis of telomeric terminal restriction fragment (TRF) length, a marker for cellular replicative history, showed that CD8(+) T cell TRF length decreased but CD4(+) T cell TRF length was stable during the course of human immunodeficiency...
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