Article
Lidocaine block of LQT-3 mutant human Na+ channels.
Circulation research - 1 Jul 1996
An R H, Bangalore R, Rosero S Z, Kass R S
Abstract excerpt
In transiently transfected mammalian cells we have identified pharmacological consequences of a naturally occurring deletion mutation, delta KPQ, of the human heart Na+ channel alpha subunit that previously has been linked to one form of the long QT syndrome, an inherited heart disease. Our resul...
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