Article
Multiple mechanisms of Na+ channel--linked long-QT syndrome.
Circulation research - 1 May 1996
Dumaine R, Wang Q, Keating M T, Hartmann H A, Schwartz P J, Brown A M, Kirsch G E
Abstract excerpt
Inheritable long-QT syndrome (LQTS) is a disease in which delayed ventricular repolarization leads to cardiac arrhythmias and the possibility of sudden death. In the chromosome 3-linked disease, one mutation of the cardiac Na+ channel gene results in a deletion of residues 1505 to 1507 (Delta KPQ...
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