Article
HIV colonizing peripheral blood monocytes follows lymphocytic isolates in shifting from NSI to SI genotype.
Archives of virology - 1 Jan 1996
Witt A, Kaiser R, Mayer A, Rolf R, Matz B, Schneweis K E
Abstract excerpt
Non-syncytium inducing (NSI) and syncytium inducing (SI) variants of human immunodeficiency virus (HIV) isolated from peripheral blood mononuclear cells (PBMC) could be definitely typed by sequence analysis of the env-gene V3 region. It was thus possible to compare the genotypes of viral variants isolated from PBMC and accompanying monocyte cultures and those derived directly from the patients' blood cells prior...
Topics
- Amino Acid Sequence
- Cells, Cultured
- Cytopathogenic Effect, Viral
- Genetic Variation
- HIV
- HIV Envelope Protein gp120
- HIV Infections
- Humans
- Leukocytes, Mononuclear
- Molecular Sequence Data
- Monocytes
