Sodium channel variants in heart disease: expanding horizons.

doi:10.1111/j.1540-8167.2006.00398.x

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Article

Sodium channel variants in heart disease: expanding horizons.

Journal of cardiovascular electrophysiology - 1 May 2006

Tan Hanno L

Abstract excerpt

Inherited arrhythmia syndromes have advanced our understanding of cardiac sodium (Na) channel function in health and disease. Long QT syndrome (LQT3) is consistently caused by increased net Na current secondary to inactivation defects, which give rise to persistent Na current. Conversely, various gating changes that ultimately result in reduced Na current may elicit Brugada syndrome, conduction disease, atrial...

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Share to Arrhythmias, Cardiac
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Share to Sodium
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Identifiers

PMID: 16686672
DOI: 10.1111/j.1540-8167.2006.00398.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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