Article
Activation and analysis of cryptic crt genes for carotenoid biosynthesis from Streptomyces griseus.
Molecular & general genetics : MGG - 28 Oct 1996
Schumann G, Nürnberger H, Sandmann G, Krügel H
Abstract excerpt
Genes encoding enzymes with sequence similarity to carotenoid biosynthetic enzymes of other organisms were cloned from Streptomyces griseus JA3933 and transformed into the colourless (non-daunorubicin producing) mutant Streptomyces griseus IMET JA3933/956/2. Cells harbouring these genes showed an orange-red pigmentation, caused by the strongly hydrophobic, membrane-bound lycopene. The cloned fragment (9 kb)...
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