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Article

Metabolic engineering of the carotenoid biosynthetic pathway in the yeast Xanthophyllomyces dendrorhous (Phaffia rhodozyma).

Applied and environmental microbiology - 1 Jul 2003

Verdoes Jan C, Sandmann Gerhard, Visser Hans, Diaz Maria, van Mossel Minca, van Ooyen Albert J J

Abstract excerpt

The crtYB locus was used as an integrative platform for the construction of specific carotenoid biosynthetic mutants in the astaxanthin-producing yeast Xanthophyllomyces dendrorhous. The crtYB gene of X. dendrorhous, encoding a chimeric carotenoid biosynthetic enzyme, could be inactivated by both single and double crossover events, resulting in non-carotenoid-producing transformants. In addition, the crtYB gene,...

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Identifiers

PMID: 12839738
DOI: 10.1128/AEM.69.7.3728-3738.2003
PMCID: PMC165150

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Source receipt: pubmed, retrieved 7 Sept 2026.

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