PCR analysis of Lewis-negative gene mutations and the distribution of Lewis alleles in a Japanese population.

Article

PCR analysis of Lewis-negative gene mutations and the distribution of Lewis alleles in a Japanese population.

Journal of forensic sciences - 1 Nov 1996

Liu Y, Koda Y, Soejima M, Uchida N, Kimura H

Abstract excerpt

Three mutations in the Lewis-negative gene, T59G, G508A and T1067A, have been detected by means of a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 149 unrelated Japanese individuals. We found three common Lewis alleles-Le (without the T59G, G508A, and T1067A mut...

Topics

Alleles
DNA
Forensic Medicine
Genotype
Humans
Japan
Lewis Blood Group Antigens
Lewis X Antigen
Mutation
Phenotype
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

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