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Article

In vitro cytotoxicity of S16020-2, a new olivacine derivative.

Investigational new drugs - 1 Jan 1996

Léonce S, Perez V, Casabianca-Pignede M R, Anstett M, Bisagni E, Pierré A, Atassi G

Abstract excerpt

S16020-2 is a new olivacine derivative which has recently shown a marked antitumor activity in various experimental models. This study was undertaken in order to measure the inhibition of the proliferation of various sensitive and resistant tumor cell lines, by S16020-2, and to obtain information concerning its mechanism of action. For a continuous exposure, S16020-2 was as cytotoxic as adriamycin (ADR) (mean...

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Identifiers

PMID: 8913838
DOI: 10.1007/BF00210788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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