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Article

Species selectivity of new siderophore-drug conjugates that use specific iron uptake for entry into bacteria.

Antimicrobial agents and chemotherapy - 1 Nov 1996

Diarra M S, Lavoie M C, Jacques M, Darwish I, Dolence E K, Dolence J A, Ghosh A, Ghosh M, Miller M J, Malouin F

Abstract excerpt

Siderophores selectively bind ferric iron and are involved in receptor-specific iron transport into bacteria. Several types of siderophores were synthesized, and growth-promoting or inhibitory activities when they were conjugated to carbacephalosporin, erythromycylamine, or nalidixic acid were investigated. Overall, 11 types of siderophores and 21 drug conjugates were tested against seven different bacterial...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8913474
DOI: 10.1128/AAC.40.11.2610
PMCID: PMC163585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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