Article
Oligomerization supports transport of a mutant secretory protein out of the endoplasmic reticulum.
European journal of cell biology - 1 Feb 1996
Losch A, Henkel K, Wagner M, Urban J, Koch-Brandt C
Abstract excerpt
To examine the transport of the single subunits of the glycoprotein complex gp80 (clusterin, apolipoprotein J), a marker protein for apical exocytosis and main secretory product of Madin-Darby canine kidney (MDCK) cells, several mutant cDNAs were constructed and expressed in the fibroblastic baby hamster kidney (BHK-21) cell line. In the absence of the second subunit the mutant proteins formed disulfide-linked...
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