Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A presenilin 1 mutation in an early onset Alzheimer's family: no association with presenilin 2.

Neuroreport - 12 Aug 1996

Poduslo S E, Herring K, Neal M

Abstract excerpt

Genes on four chromosomes have been associated with Alzheimer's disease. Mutations in the chromosome 14 gene (S182 or presenilin 1) have been linked with an aggressive very early form of the disease while mutations in a chromosome 1 gene (STM2 or presenilin 2) have been linked with Volga German kindreds. When we screened our Alzheimer's patients for the first mutations reported, we only found one in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alzheimer Disease
Share to Autoradiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Sequence

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Presenilin-2

Source

Identifiers

PMID: 8905716
DOI: 10.1097/00001756-199608120-00033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A presenilin 1 mutation in an early onset Alzheimer's family: no association with presenilin 2.PMID 8905716Read ↗

Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype.Semantic proximity Read ↗

A polymorphism in the presenilin 1 gene does not modify risk for Alzheimer's disease in a cohort with sporadic early onset.Semantic proximity Read ↗

Presenilin-2 mutation and polymorphism in Japanese Alzheimer disease patients.Semantic proximity Read ↗

Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.Semantic proximity Read ↗

A presenilin 1 mutation in the first case of Alzheimer's disease.Semantic proximity Read ↗

[Presenilin-1 (S182) causative gene of early-onset familial Alzheimer's disease].Semantic proximity Read ↗

Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease.Semantic proximity Read ↗

Molecular genetics of Alzheimer's disease: presenilin 1 gene analysis in a cohort of patients from the Poznań region.Semantic proximity Read ↗

A pedigree with a novel presenilin 1 mutation at a residue that is not conserved in presenilin 2.Semantic proximity Read ↗

Novel Presenilin 1 Mutations Associated With Early Onset of Dementia in a Family With Both Early-Onset and Late-Onset Alzheimer DiseaseSemantic proximity Read ↗

F175S change and a novel polymorphism in presenilin-1 gene in late-onset familial Alzheimer's disease.Semantic proximity Read ↗

A novel presenilin 1 mutation resulting in familial Alzheimer's disease with an onset age of 29 years.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.