Article
Effects of 2-deoxy-d-glucose on the functional state of the rat myoblast GLUT 1 transporter.
Biochemistry and molecular biology international - 1 Oct 1996
Mesmer O T, Lu Z, Xia L, Lo T C
Abstract excerpt
Based on the rationale that internalized 2-deoxy-D-glucose (dGlc) is toxic to cells, glucose transport (GLUT) defective myoblast mutants have been isolated by their ability to grow in glucose-free medium containing dGlc. Recent studies revealed that the GLUT 1 transport process was activated when GLUT 3-GLUT 4-mutants were grown in glucose-free medium. It was therefore puzzling why these GLUT3-GLUT4-myoblasts...
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