Article
Age-dependent penetrance and mapping of the locus for juvenile and early-onset open-angle glaucoma on chromosome 1q (GLC1A) in a French family.
Human genetics - 1 Nov 1996
Meyer A, Béchetoille A, Valtot F, Dupont de Dinechin S, Adam M F, Belmouden A, Brézin A P, Gomez L, Bach J F, Garchon H J
Abstract excerpt
The GLC1A locus for autosomal dominant primary open-angle glaucoma (POAG) with juvenile onset (before 20 years) has been mapped to chromosome 1q21-q31. Recently, a French-Canadian family was described in which both juvenile-onset and middle-age or early-onset POAG were observed and linked to GLC1...
Topics
- Adolescent
- Adult
- Age Factors
- Canada
- Child
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Female
- France
- Genetic Linkage
- Glaucoma, Open-Angle
- Haploidy
- Humans
- Lod Score
- Male
- Middle Aged
- Pedigree
- Phenotype