Article
Clinical phenotype of juvenile-onset primary open-angle glaucoma linked to chromosome 1q.
Ophthalmology - 1 May 1996
Johnson A T, Richards J E, Boehnke M, Stringham H M, Herman S B, Wong D J, Lichter P R
Abstract excerpt
PURPOSE: Recent reports have suggested that a gene responsible for juvenile-onset primary open-angle glaucoma exists on the long arm of chromosome 1 (1q). This report describes a previously unpublished family (UM:JG3) in which juvenile-onset glaucoma is segregating in an autosomal dominant manner...
Topics
- Adolescent
- Adult
- Age of Onset
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- DNA
- Female
- Genetic Linkage
- Genetic Markers
- Glaucoma, Open-Angle
- Humans
- Intraocular Pressure
- Lod Score
- Male
- Middle Aged
- Pedigree
- Phenotype
- Polymerase Chain Reaction