Article
Prion protein genotype and pathological phenotype studies in sporadic Creutzfeldt-Jakob disease.
Neuropathology and applied neurobiology - 1 Aug 1996
MacDonald S T, Sutherland K, Ironside J W
Abstract excerpt
A comparative semi-automated morphometric study was performed on the distribution of prion protein, spongiform change and astrocytosis in the brains of nine cases of sporadic Creutzfeldt-Jakob disease of differing genotype at the methionine-valine polymorphism at codon 129 of the prion protein gene. Custom-designed image analysis software was used to produce objective figures for each of the different...
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