Article
In vitro production and transplantation of immunologically active skin equivalents.
Laboratory investigation; a journal of technical methods and pathology - 1 Oct 1996
Rouabhia M
Abstract excerpt
In this study, we produced in vitro epidermal equivalents (EE) and skin equivalents (SE) with and without spleen lymphocytes. These skin substitutes were used for in vitro and in vivo (after isograft) histologic studies of cell and extracellular matrix organization and for protein synthesis. Then, using spleen lymphocytes in syngeneic and allogeneic SE, we assessed the immunogenicity of these skin substitutes...
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