Article
Abnormalities of sex differentiation.
Hormone research - 1 Jan 1996
Nawata H, Takayanagi R, Yanase T, Ikuyama S, Okabe T
Abstract excerpt
Sex differentiation is determined by a cascade of events proceeding from chromosomal sex to the completion of sexual maturation at puberty. Many factors involved in this cascade have been identified. Here we focus on DAX-1, androgen receptor and cytochrome P450c17, and discuss their functions in sex differentiation. We analyzed the DAX-1 genes of two unrelated Japanese patients with congenital adrenal hypoplasia...
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