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Genetic variation in neuraminidase genes of influenza A (H3N2) viruses.

Virology - 1 Oct 1996

Xu X, Cox N J, Bender C A, Regnery H L, Shaw M W

Abstract excerpt

Nucleotide sequences of the neuraminidase (NA) genes of 33 influenza A (H3N2) epidemic strains isolated between 1968 and 1995 were analyzed to determine their evolutionary relationships. Phylogenetic analysis using the DNA maximum-likelihood method indicates that the NA genes of recent H3N2 field strains, like their hemagglutinin genes (HA), have evolved as two distinct lineages represented by the vaccine...

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PMID: 8862412
DOI: 10.1006/viro.1996.0519

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