Article
Molecular evolution of HA1 in influenza A (H3N2) viruses isolated in Japan from 1989 to 2006.
Intervirology - 1 Jan 2008
Saitoh Mika, Kimura Hirokazu, Kozawa Kunihisa, Shoji Akira
Abstract excerpt
OBJECTIVES: To evaluate the trend of phylogenetic evolution among influenza A (H3N2) viruses isolated in Gunma and A (H3N2) vaccine strains, we studied the transition of gene mutations and amino acid substitution of the sites A and B in HA1 during long-term seasons. METHODS: A total of 15 A (H3N2) strains were obtained from patients in Gunma, Japan, during the 1989-2006 seasons. A partial HA1 gene was amplified...
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