Article
Spread of predominant neuraminidase and hemagglutinin co-mutations in the influenza A/H3N2 virus genome.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Mar 2018
Chong Yong, Ikematsu Hideyuki
Abstract excerpt
Genetic variation of influenza neuraminidase (NA), unlike for hemagglutinin (HA), has not been fully characterized. Therefore, we determined the relation between mutations in the NA and HA genome segments of 205 influenza A/H3N2 viruses isolated from patients in Japan during the five seasons from 2010 to 2015. The amino acid (AA) sequences of the NA and HA proteins in these isolates were then determined. In the...
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